Getting
Started Guides

Step-by-step guides to help you get started with your new device

Find out more

For Heathcare Professionals

For use by physicians

  • Last updated: 29 July 2025
  • Est. reading time: 5 minutes
  • SIBO and weight gain

  • Can SIBO make you gain weight? The short answer is, it’s complicated. SIBO is associated with various symptoms, including weight gain. Studies have shown that the risk of SIBO is about two times higher in people with obesity. The relationship between SIBO and weight gain can be influenced by several factors. In this article, we will walk you through the hidden link between SIBO and weight gain.

  • Est. reading time: 5 minutes
  • SIBO and weight gain

  • Can SIBO make you gain weight? The short answer is, it’s complicated. SIBO is associated with various symptoms, including weight gain. Studies have shown that the risk of SIBO is about two times higher in people with obesity. The relationship between SIBO and weight gain can be influenced by several factors. In this article, we will walk you through the hidden link between SIBO and weight gain.

If you suspect you have SIBO, it’s important to consult a medical professional, as as the condition shares similarities with other digestive disorders. If diagnosed or managing digestive challenges, the FoodMarble breath tester can support you in tracking and managing your symptoms effectively.

 

What is SIBO?

Small Intestinal Bacterial Overgrowth (SIBO) is a condition characterized by having too many of the wrong bacteria in the wrong place i.e. the small intestine. Under normal circumstances, the small intestine has a relatively low population of bacteria compared to the large intestine. When this balance is disrupted, and excessive bacteria colonize the small intestine, it can lead to various symptoms, including weight gain.

Why does SIBO cause my weight gain?

 

SIBO-Induced Malabsorption

An impaired digestion and absorption of nutrients  is one of the reasons for the association between SIBO and weight gain. The overgrowth of bacteria in the small intestine can interfere with the normal digestion of carbohydrates, proteins, and fats, leading to malabsorption. This malabsorption can result in nutritional deficiencies, which may trigger increased appetite and subsequent weight gain as the body tries to compensate for the lack of essential nutrients.

 

Insulin Resistance in SIBO

SIBO may be associated with lower levels of insulin release and impaired glycemic control. Insulin resistance can promote weight gain by hindering the body’s ability to efficiently use glucose as an energy source, which can lead to increased fat storage.

 

Inflammation in SIBO

The presence of bacteria in the small intestine can trigger inflammation and promote metabolic dysfunction. The imbalanced gut microbiota can produce endotoxins which can enter the bloodstream and activate inflammatory pathways. Chronic inflammation is associated with weight gain and can contribute to the development of metabolic disorders, including obesity and insulin resistance.

How does gut health impact weight?

Beyond SIBO, the relationship between gut health and weight gain extends to the overall balance of the gut microbiota. The gut microbiota plays a vital role in various aspects of human health, including metabolism and weight regulation. An imbalance in the gut microbiota, known as dysbiosis, has been linked to weight gain and obesity.

Dysbiosis can occur due to factors such as a poor diet high in processed foods and sugar, antibiotic use, stress, and lack of physical activity. When the gut microbiota is imbalanced, it can affect the way the body metabolizes food, leading to increased energy extraction from food, increased fat storage, and decreased insulin sensitivity.

Moreover, the gut microbiota influences appetite regulation through its interactions with the gut-brain axis. Certain gut bacteria can produce signaling molecules that influence hunger and satiety signals, ultimately impacting food intake and body weight. Additionally, an imbalanced gut microbiota can affect the production of hormones involved in appetite regulation, such as leptin and ghrelin, further contributing to weight gain.

Final Thoughts: Can understanding SIBO & gut health help you manage weight gain?

Of course! SIBO and overall gut health have significant implications for weight gain. The overgrowth of bacteria in the small intestine in SIBO can disrupt digestion, promote inflammation, and contribute to metabolic dysfunction, all of which can lead to weight gain. Furthermore, an imbalanced gut microbiota, characterized by dysbiosis, can impact energy metabolism, appetite regulation, and hormone production, influencing body weight. Understanding and addressing these relationships are crucial for managing weight gain and promoting overall gut health. It’s also important to remember that  while SIBO is treatable, it has a tendency to recur, making an understanding of underlying causes vital in preventing its return.

Take Control of Your Next Steps

If you’re grappling with unsettling symptoms like bloating, abdominal pain, or belching, it might be time to consider SIBO as a potential culprit. Here are your next steps to regain control:

Consult Your Doctor: If you are experiencing any of the symptoms commonly associated with SIBO, your first port of call should be consulting your healthcare provider. They can provide professional advice and may recommend a breath test for more accurate diagnosis. If you are based in the US, FoodMarble’s MedAIRE has you covered for at-home SIBO testing.

Your At-Home Gut Guide – FoodMarble AIRE2: Looking for a flexible way to monitor your gut health? Our FoodMarble AIRE 2 allows you to conduct breath tests at home, whenever it’s convenient for you. With AIRE 2, you can track daily fluctuations in your gut by testing your breath and analyzing hydrogen and methane levels. It’s like having a personal gut health monitor to help you identify which foods trigger your symptoms and manage them more effectively. 

For a real-life take on this journey, don’t miss out on “My SIBO Journey: Áine’s Story”.

Frequently Asked Questions
about SIBO and Weight Gain

Yes, SIBO can lead to weight gain in some people. This happens due to factors like SIBO-induced malabsorption, inflammation, insulin resistance, and disrupted appetite regulation.

Your gut microbiota plays a major role in how your body handles energy, hunger, and fat storage. When your gut is imbalanced, a state known as dysbiosis can lead to increased calorie extraction from food, disrupted hormone signaling, and a higher risk of weight gain or obesity.

Yes. SIBO can disrupt digestion, trigger inflammation, and affect appetite, all of which may contribute to weight gain. FoodMarble uses breath testing technology to measure hydrogen and methane levels – key indicators of SIBO. By tracking these gases, you can better understand what foods may cause your SIBO symptoms, take steps to restore gut balance, and make informed choices that support healthier digestion and weight management.

FoodMarble AIRE 2 lets you track hydrogen and methane levels in your breath, helping you monitor fermentation and identify how your body reacts to different foods. With daily testing, you can gain insights into symptom triggers and support better food choices. It helps you manage SIBO easier and feel more in control of your gut health and weight.

Barry Mc Bride

  • 9 January 2024
  • Share this
  • FoodMarble
  • FoodMarble
  • FoodMarble
  • FoodMarble

Discover More

Search recipes, articles, stories: