GLP-1 medications work partly by slowing digestion, and for many people that change affects the gut in noticeable ways. Digestive side effects are common, especially early on, and can range from mild to disruptive.
Understanding why these symptoms happen, using practical strategies to manage them, and tracking patterns over time can make it easier to navigate treatment. With the right information and clinical support, many people are able to find a balance that works for both metabolic health and digestive comfort.
FoodMarble is a leader in digestive health, supporting healthcare practices and helping individuals better understand their gut health. Using the same hydrogen and methane technology as clinical breath tests, FoodMarble makes lab-grade breath testing accessible from the comfort of home.
Our technology helps people with IBS or persistent gut symptoms identify food triggers and understand their personal tolerance levels. It can also support people managing small intestinal bacterial overgrowth (SIBO) by helping them track whether their current protocol is working, reintroduce foods with greater confidence, and monitor for recurrence over time.
1) Discontinuation and Reinitiation of Dual-Labeled GLP-1 Receptor Agonists Among US Adults With Overweight or Obesity
PubMed Central (PMC).
https://pmc.ncbi.nlm.nih.gov/articles/PMC11786232/
2) Clinical Recommendations to Manage Gastrointestinal Adverse Events in Patients Treated with GLP-1 Receptor Agonists: A Multidisciplinary Expert Consensus
PubMed Central (PMC).
https://pmc.ncbi.nlm.nih.gov/articles/PMC9821052/
3) GLP-1 Diabetes and Weight-Loss Drug Side Effects: “Ozempic face” and more
Harvard Health Publishing, Feb 5, 2024.
https://www.health.harvard.edu/staying-healthy/glp-1-diabetes-and-weight-loss-drug-side-effects-ozempic-face-and-more
4) Rao SSC, et al. Small Intestinal Bacterial Overgrowth: Clinical Features and Therapeutic Management.
Gastroenterology Clinics of North America.
5) Pimentel M, et al. Methane, a Gas Produced by Methanogens, Slows Intestinal Transit and Is Associated With Constipation.
The American Journal of Gastroenterology.