Measuring postprandial hydrogen shows potential as a means of differentiating patients with chronic GI symptoms from healthy controls and may be useful in monitoring patients before, during, and after treatment.
Validation of a Hand‐Held Point‐of‐Care Device to Measure Breath Hydrogen and Its Utility in Detecting Response to Antibiotic Treatment Barahona G. et al. Digestive Diseases and Sciences., July 2024.
An independent external validation comparing AIRE to an existing breath hydrogen analyser for the diagnosis of lactose malabsorption.
Validity of a Portable Breath Analyser (AIRE) for the Assessment of Lactose Malabsorption. Shrestha A et al., Nutrients 2019.
AIRE was compared to the gold-standard clinical device to detect how well a particular carbohydrate was absorbed. There was 100% diagnostic agreement between the two devices.
A Pilot Validation Study Of An At-Home Hydrogen Breath Test Device. Gut. 2019; 68 (Suppl 2):A1–A269.Breath testing is a non-invasive, cost-effective diagnostic tool used to evaluate a range of digestive conditions. It’s use is endorsed by the world’s leading gastroenterological organisations.
Breath testing represents an important, simple and safe test to diagnose carbohydrate maldigestion syndromes and small intestinal bacterial overgrowth (SIBO).
Hydrogen and Methane-Based Breath Testing in Gastrointestinal Disorders: The North American Consensus 2017
We suggest the use of breath testing for the diagnosis of SIBO in patients with IBS...in symptomatic patients with suspected motility disorders...and in patients with constipation.
ACG Clinical Guideline: Small Intestinal Bacterial Overgrowth 2020
Breath testing (lactulose and glucose) is...used to diagnose SIBO and appears to identify subjects likely to respond to treatment.
AGA Clinical Practice Update on Small Intestinal Bacterial Overgrowth: Expert Review 2020
Breath tests are non-invasive, relatively simple to perform and safe diagnostic tools, which can be used both in adults and in children. The results are considered helpful in the evaluation of common abdominal symptoms such as bloating, flatulence, abdominal pain, and diarrhea...
European guideline on indications, performance, and clinical impact of hydrogen and methane breath testing adult and pediatric patients 2022Patients with a positive breath test are more than twice as likely to respond to treatment than those treated empirically. SIBO relapse is common, MedAIRE 2 makes retesting easy.
Those with methane-predominant SIBO are more likely to have constipation. Methane severity correlates to severity of constipation. Measuring methane enables more personalised treatment.
Food is perceived as a symptom trigger for 50-84% of IBS patients. Using MedAIRE 2 allows easy assessment of common food intolerances like fructose, lactose, inulin and sorbitol.
Jay Pasricha MD
Chair of Medicine,
Mayo Clinic, Arizona
Bill Chey MD
Chief of GI and Hepatology,
Michigan Medicine
Lin Chang MD
Professor, Vice-Chief,
Division of Digestive Diseases, UCLA
Reed Hogan MD
Physician Executive,
GI Alliance
Joel Brill MD
Expert in US healthcare
reimbursement & strategy
Neil Parikh MD
Chief Innovation Officer, CTGI,
Chief of GI Hartford Hospital